Autoimmunity and the risk of cancer Essay Example | Topics and Well Written Essays - 1000 words

Autoimmunity and the risk of cancer - Essay Example Immunological mechanism refers to the collection of human cells which perform the fundamental function of providing immunity to diseases. The mechanism can be defined as the body’s defence mechanism, as it provides the body with resistance from infection by foreign microbes (Singh et al. 2014). Immunological mechanism can be effectively induced within the human body through vaccination process, which introduces disease resistance cells into the body. The defence mechanisms of the human body possess the capability to adapt and recognise pathogens through a period of time. The capability to adapt leaves an immunological memory following initial detection of pathogens. On the other hand pathogens also have adaptive capabilities which make them difficult to detect. The process of acquired or adaptive immunity has been the basis for development of vaccines, for different pathogens.Cancer refers to a malignant neoplasm caused by uncontrollable division and growth of cells, resulting in malignant tumour which invades nearby body parts. Cancer constitutes of numerous diseases which result in unregulated growth of cells within the human body(Penn 1982). Causes of these diseases remain diverse as the diseases with few being understood by medical practitioners. Many factors have been identified as increasing the risk for cancer development, including tobacco use, exposure to radiation, genetic factors, and infections, among many others. The characteristic presence of cancer involves damage to genes.

Formal Learning and Informal Learning Dissertation

Formal Learning and Informal Learning - Dissertation Example Research Design 38 3.2. Research Methodology 39 3.3. Method of Data Collection 40 3.3.1. Selection of Documents 40 3.3.2. Qualitative Research 41 3.4. Data Analysis 43 3.5. Justification of the Choice of Methodology 44 3.6. Role of the Researcher 45 3.7. ETHICAL ISSUES/CONSTRAINTS/VALUES OF THIS RESEARCH 46 3.8. Potential Value of this Research 47 Chapter 4 Findings and Discussions 48 4.0. Introduction 48 4.1. Findings and Discussions 48 4.1.1. Better Appreciation of Informal Learning in the Work Place and Central Role of Employees 49 4.1.2. The More Effective Approach 51 4.1.3. The Learning Approaches 55 4.1.4. Kinds of Information 61 4.1.5. The Factors 63 4.1.6. The Balance 64 Summary 68 Chapter 5 Conclusion, Limitations and Recommendations 69 5.0. Conclusion 70 5.1. Limitations/Possibilities 72 5.2. Recommendations 72 References: 75 Appendix 1 81 Fig. 1 p. 6 Fig. 2 p. 14 Fig. 3 p. 21 Fig. 4 p. 30 Fig. 5 p. 49 Table 1 p. 16 Chart 1 p. 55 Chart 2 p. 56 Chart 3 p. 57 Chart 4 p. 58 Ch art 5 p.59 Chart 6 p. 61 Chart 7 p.62 Chapter 1 Introduction 1.0. Introduction Globalisation opens a new a paradigm in the economic interactions among nations around the globe (Fisher, 2003). Generally, this unique phenomenon enables people across the globe to access services and goods from different countries with ease (Soros, 2002), thus, paving fro exchanges not only for goods and services, but also of ideas, knowledge and identity as greater mobility are experienced by people (Peet, 2003; Suarez-Orozco and Qin-Hilliard, 2004). In addition, globalisation creates tougher competition in the global market economy, challenging organisations to continuously come up with products and services that genuinely respond to the changing needs and demands of the 21st century clients (Suarez-Orozco and Qin-Hilliard, 2004). Responding to the challenge pose by globalisation, firms have come up with strategies and developments that will endow organisations with the opportunity in creating a niche and surviving the stringent global market competition. One of the most noteworthy development in the recent period is the recognition of the central importance of the role of employees in attaining the goals of the company (Armstrong, 2006). The human factor in the organisation is deemed as the human capital essential for the success of the organisation (Beer et al., 1984; Bontis et al., 1999; Caldwell, 2004; de Meneses and Woods, 2008; Ramirez, Guy, and Beale 2007). In effect, the collective knowledge, skills, learning, abilities and experiences that are deployed by the employees in the performance of their functions is crucial for the success of the firm and a primary source of the organisation’s strategic advantage (Armstrong, 2006). As such, in the last few decades, much scholarly work have been undertaken to elucidate the various concepts that are inherent in human capital . One of the subject matters that have been given ample consideration is learning in the workplace . Learning is considered as a spectrum of formal learning, informal learning and non-formal learning (Cook and Smith, 2004). A person may move from one section of the spectrum to another without diminishing the significance and influence of learning and its consequences to the individual. This is possible because learning is a process of awareness, reflection, association and application that involves transforming experience and knowledge into functional learning

During the 20th century, african americans Civil Rights received Essay

During the 20th century, african americans Civil Rights received profound social and cultural change - Essay Example Revolution and other forceful approaches were the best options for the black Americans to express their plights. In 1956, Martin Luther King Jr. confronted methodological and ideological challenges through advocacy and Civil Rights Movements. The challenges focused on philosophical key tenets that formed the basis of Civil Rights Movement. The first sentiments promoted by the advocates of black power were integration and non-violence. Various SNCC’s and CORE’s black activists advocated re-evaluation of the influence created by civil rights proponents. White advisors as murders of black workers took place without being noticed (Ongiri 102). Ideologies of black activists and tenets of Black Power ideologies prompted a new sense of pride and identity. Consequently, black Americans insisted that America refer to them as Afro-Americans, not as Negroes. Further, in 1960’s, black Americans boasted of the privilege of adopting a similar dressing code to that of white Americans. The 1963 match to Washington was iconic in the history of advocacy for human rights in America. Organizers from Greenwood Mississippi, Willie Ricks, who swore to enhance Black Power ideologies to a different level in 1966. Ricks instituted, among blacks, the spirit of getting armed and ready for confrontations against white supremacists such as the Ku Klux Klan. As a result, black Americans armed themselves against the Ku Klux Klan armed terrorists and prepared for the worst including death. Finally, the activities of Klan within the community ceased. In 1966, the existence of Black Panther was a notable influence that prompted reforms. It informed Black Power ideologies and best practices about their broadest public platforms. The Black Panthers advocated through all necessary principles to eliminate and eradicate racial inequality that existed between black and white Americans. Police brutality against black neighborhoods reduced. Leather jackets, light blue shirts, and black power

Formal Learning and Informal Learning Dissertation

Formal Learning and Informal Learning - Dissertation Example Research Design 38 3.2. Research Methodology 39 3.3. Method of Data Collection 40 3.3.1. Selection of Documents 40 3.3.2. Qualitative Research 41 3.4. Data Analysis 43 3.5. Justification of the Choice of Methodology 44 3.6. Role of the Researcher 45 3.7. ETHICAL ISSUES/CONSTRAINTS/VALUES OF THIS RESEARCH 46 3.8. Potential Value of this Research 47 Chapter 4 Findings and Discussions 48 4.0. Introduction 48 4.1. Findings and Discussions 48 4.1.1. Better Appreciation of Informal Learning in the Work Place and Central Role of Employees 49 4.1.2. The More Effective Approach 51 4.1.3. The Learning Approaches 55 4.1.4. Kinds of Information 61 4.1.5. The Factors 63 4.1.6. The Balance 64 Summary 68 Chapter 5 Conclusion, Limitations and Recommendations 69 5.0. Conclusion 70 5.1. Limitations/Possibilities 72 5.2. Recommendations 72 References: 75 Appendix 1 81 Fig. 1 p. 6 Fig. 2 p. 14 Fig. 3 p. 21 Fig. 4 p. 30 Fig. 5 p. 49 Table 1 p. 16 Chart 1 p. 55 Chart 2 p. 56 Chart 3 p. 57 Chart 4 p. 58 Ch art 5 p.59 Chart 6 p. 61 Chart 7 p.62 Chapter 1 Introduction 1.0. Introduction Globalisation opens a new a paradigm in the economic interactions among nations around the globe (Fisher, 2003). Generally, this unique phenomenon enables people across the globe to access services and goods from different countries with ease (Soros, 2002), thus, paving fro exchanges not only for goods and services, but also of ideas, knowledge and identity as greater mobility are experienced by people (Peet, 2003; Suarez-Orozco and Qin-Hilliard, 2004). In addition, globalisation creates tougher competition in the global market economy, challenging organisations to continuously come up with products and services that genuinely respond to the changing needs and demands of the 21st century clients (Suarez-Orozco and Qin-Hilliard, 2004). Responding to the challenge pose by globalisation, firms have come up with strategies and developments that will endow organisations with the opportunity in creating a niche and surviving the stringent global market competition. One of the most noteworthy development in the recent period is the recognition of the central importance of the role of employees in attaining the goals of the company (Armstrong, 2006). The human factor in the organisation is deemed as the human capital essential for the success of the organisation (Beer et al., 1984; Bontis et al., 1999; Caldwell, 2004; de Meneses and Woods, 2008; Ramirez, Guy, and Beale 2007). In effect, the collective knowledge, skills, learning, abilities and experiences that are deployed by the employees in the performance of their functions is crucial for the success of the firm and a primary source of the organisation’s strategic advantage (Armstrong, 2006). As such, in the last few decades, much scholarly work have been undertaken to elucidate the various concepts that are inherent in human capital . One of the subject matters that have been given ample consideration is learning in the workplace . Learning is considered as a spectrum of formal learning, informal learning and non-formal learning (Cook and Smith, 2004). A person may move from one section of the spectrum to another without diminishing the significance and influence of learning and its consequences to the individual. This is possible because learning is a process of awareness, reflection, association and application that involves transforming experience and knowledge into functional learning

Public participation in Guelph landfill search process Essay

Public participation in Guelph landfill search process - Essay Example Anyone can play a role in rebuilding the environment† (par. 7). This sounds like a lovely idea, and a very creative way to turn what is essentially a controversial garbage dump into something more positive†¦something the public can enjoy and be proud of. The City’s choice not to relocate the landfill and go with a more environmentally sound decision was a wise one, helped enormously by public input. The Implication: Social Risk vs Economics The City of Guelph had for some time known it would have to deal with the issue of a needed landfill. In fact from 1987 discussions had been sporadically on-going with little progress, the reality being that no one wants a landfill in their backyard for all of the obvious reasons. In January of 1993 a proposed dump site north of Guelp was eliminated from further consideration after opponents managed to convince city council to throw out almost three years of work that had cost nearly $3 million. It was the beginning of a back and forth battle that would discourage county involvement and place the onus of burden on the city of Guelph. The search, beginning in 1994, would be controversial, intense and difficult. Based on records the intension of including public opinion and that and of others was, at least at first, well meaning. Ali (1999) in his study of the project writes, â€Å"In order to avoid the pitting of the public against the technical consultants that had occurred in a previously unsuccessful search, Guelph City Council wished to adopt a more inclusive process in which all members of the community could voluntarily participate† (p. 1). To this end the Landfill Search Group (LSG), a Community Advisory Subcommittee of varied professionals and the (CASC), or Neighbourhood Liaison Groups made up of volunteers from all walks of life from the community and ostensibly representing the public. It would seem that things would go smoothly, but that was not the case and the public, suspicious of how t he groups were selected and would perform, formed their own counter groups who, at the outset, were set against the landfill. After the LSG announcement of five potential sites, other neighbourhood groups were formed against the landfill for environmental reasons and surprisingly, on the basis that the sites which were being considered were all in lower economic areas. In essence, the latter complaints were â€Å"primarily on the basis of social equity† (Ali, 1999, p. 1) and the fact that the area was already home of a good share of the industry of the city. All of the groups came up with a list of 48 criteria on which the selection would be based, prioritized by the public which, in the end, promoted a site considerate of public health and the environment. From the beginning much of the controversy centered upon the components of priority ranking of the various aspects of the decision making process concern acceptable tradeoffs â€Å"between economic and environmental impac ts†¦to both the community and to the City† (Ali, 1999, p. 1). The business community favored sacrificing environmental concerns [groundwater contamination] for business interests, while other groups set on protecting the environment held fast. In the end, site selection was placed in the precarious position of a quid pro quo. As Ali (1999) quoting officials

Michael Smyth vs. Pillsbury Company. Essay Example for Free

Michael Smyth vs. Pillsbury Company. Essay STYLE: Michael Smyth vs. Pillsbury Company. COURT: United States District Court of Pennsylvania. CITATION: 914 F. Supp. 97; 1996 U.S. Dist. LEXIS 776; 131 Lab. Cas. (CCH) P58, 104; 11 I.E.R. Cas. (BNA) 585. ISSUE: Can an employer be accused of violating public policy, tortuously invading privacy and subsequently be estopped from firing or discharging an at will employee, if for the purpose of company’s interest, it monitor an employee’s email communications over the company’s email system just to find them contrary to company’s interest? FACTS: Plaintiff, a manager at defendant’s company had work email account with access from home. Plaintiff was assured by defendant that email communication is private and confidential with no messages being intercepted and used employment termination. Plaintiff in reliance to promise to its detriment used work email system to make threatening email comments with supervisor was intercepted and employment was terminated. Court ruled in favor of Defendant as it was not evident if termination threatened or violated a clear mandate of public policy or Plaintiff’s common law right to privacy. HOLDING: An employer cannot be accused for violating public policy, privacy and/or discharging an employee according to restatement definition of tort of intrusion upon seclusion. LAW: Restatement (Second) of Torts  § 652B: Liability only attaches when the intrusion is substantial and would be highly offensive to the ordinary. Unless an employee identifies a specific expression of public policy violated by his discharge, it will not be labelled as wrongful and within the sphere of public policy†. EXPLANATION: The clear mandate of public policy must strike at the heart of a citizen’s social right, duties and responsibilities. Plaintiff was not fired for serving on jury duty, for prior conviction or for reporting violation of federal regulations to NRC. Plaintiff’s alleged unprofessional communication over email system utilized by entire company diminishes expectation of privacy. Plaintiff was not asked to disclose personal information by defendant. JUDGEMENT: The motion of the defendant to dismiss was granted. The complaint was dismissed with prejudice

Sophiatown in the 1950s

Sophiatown in the 1950s Sophiatown is a suburb in Johannesburg, South Africa. It is located on a Johannesburg ridge called Melville Koppies. Sophiatown is an example of how apartheid was bad for the native inhabitants and that it had to go. Before apartheid Sophiatown was established for Europeans, but as the city Johannesburg developed and a sewage dump nearby, the Europeans left and the land was then rented by the native people. The natives were allowed to settle in Sophiatown because it was near the sewage dump and the Europeans in the city didnt want the miners to settle within the city limits. Sophiatown shows how South Africa developed under apartheid. The apartheid caused multiracial communities in Sophiatown that developed to become multicultural. Sophiatown was the only place the people could rent themselves in Johannesburg that was not owned by the government. Apartheid was the ruling of Europeans in South Africa over the natives during 1948-1994. The Europeans found that South Africa had rich res ources, especially gold, for mining and that they could use the labor of the natives to get it. They developed a government system, Nationalist Party, which kept the natives down to maintain the European authority which was known as Afrikaners. The population of South Africa migrated to the sites the Europeans were building to mine the resources but they were required to abide by discriminatory laws made by the Europeans. Sophiatown developed as Johannesburg did and helped to end apartheid. Sophiatown was originally a farm outside of Johannesburg bought by Hermann Tobiansky. Tobiansky named the suburb after his wife Sophia, and the suburb was only for Europeans. However, when a sewage dump was built nearby the Europeans didnt want to settle there and the owner allowed natives and other nationalities to settle there. During the beginning of the first world war natives moved to cities for the jobs in mining and factory work. During and after the first world war the Johannesburg City Council (JCC) passed slum clearance programs, which removed natives from the inner parts of Johannesburg. These people had nowhere to go so they moved to Sophiatown (SA History). Because of the multiracial communities, the music culture of Sophiatown continued to develop in spite of the apartheid rule. During the 1920s the slums of Johannesburg were packed with hundreds of people that set up clubs like the Marabi where most of the indigenous jazz of South Africa developed. The specific styles in Johannesburg were known as Tsaba-Tsaba which was a working class form of dance music. However, during the 1930s when the JCC was clearing out the slums, people had to move to Sophiatown where shebeens and dance-parties were still held, but the South African Jazz was influenced by the American Jazz on the radio stations in the shanty town. Because of the American influence groups in Sophiatown would play American swing instead of the old Jazz from Johannesburg. The old Jazz came back and was combined with the new American swing to create Kwela which was basically penny whistling. The kwela culture in Sophiatown also developed different dance forms, one of which was pha ta-phata or touch touch. The kwela culture was part of the shady part of Sophiatown, people would gamble. Since the people were raided by the police, people would set up look outs and when the police were nearby the people would put up all evidence and they would play kwela as an excuse for a gathering. During the 1950s kwela culture had piano and saxophone added to the instrumentation and it became Majuba. The name was eventually changed to Mbaqanga (SA History). The culture of Sophiatown was greatly influenced by the theatres Odin and Balanskys. The Balanskys theatre played many movies from the United States. The gangs of Sophiatown patterned their behavior after the gangsters in the movies they saw. The Tsotsis gang based their dress patterns and language after Street with No Name, they dressed in trench coats like in the movies and they used slang like Remember guys, Im de brains of dis outfit!(SA history). Other gangs in Sophiatown were named after famous foreign parties like the Nazis and foreign gangsters like the American Vultures (Sophiatown) The day to day living of Sophiatown was difficult and was based on any way that they could survive. Because the people were forced out of the city to Sophiatown, the people lived in close quarters and poor living conditions. In Sophiatown the natives were not required by the government to acquire a permit. The black land owners had to pay huge mortgage so they allowed others to settle in their backyards. The population grew exponentially because of this and people had to become tenants and subtenants on other peoples backyards. Since they were usually poor, the people who migrated to Sophiatown had to build houses out of metal sheets and excess materials. Since all the adult males were working in the mines, the adolescents were unsupervised and could do whatever they wanted to do and joined gangs as well as common theft and murder. The women in Sophiatown had to find work as prostitutes or they worked as alcohol queens in shebeens. Shebeens were similar to speak-easies in the United States, they were places that people could drink alcohol and talk about local problems. Shebeens were usually held in the queens homes with bands playing for entertainment. Shebeens were risky business since police could raid and arrest anyone within the Shebeens and the methods for brewing alcohol were dangerous at the time. However, Shebeens werent all bad they were places were politicians met and discussed ideas to people, and they werent all dirty dark rooms but were sometimes clean respectable places with imported furniture (Hannerz). The most important event in Sophiatown was the removal and destruction of Sophiatown. The head of the South African government was the Nationalist Party which controlled the JCC. Because the Nationalist Party was part of the apartheid, it passed laws to suppress the natives in Sophiatown and they rationalized this because Johannesburg was growing and the black neighborhoods were getting too close to the white suburbs. The removal of the residents of Sophiatown was organized by the Native Resettlement Board, which was a more localized part of the NP. The people were moved to Soweto where the NP established a housing system from a census about the population within the shanty town, but they didnt know about the housing that was being provided which was generally better than the current living quarters of the average person in Sophiatown. The people refused to leave and the slogan of the people was ons dak nieà ¢Ã¢â€š ¬Ã‚ ¦.ons phola hierso which meant we are not moving We are staying (SA history). The people rebelled and used guns and explosives to keep the government officials from forcing them out, but the government eventually won and forced thousands to move to the meadowlands of Soweto. The destruction of Sophiatown continued from 1955-1960 during which the people were forced to move and their homes were bulldozed. The removals in Sophiatown brought peoples attention to the apartheids unjust rule, because it was the only place the government didnt strictly regulate. After the removals political leaders made speeches specifically naming the incident to inspire people to rise against the apartheid rule. One of the people who made such speeches about Sophiatown was Nelson Mandela. As well as the revolts in Sophiatown, people in Soweto were revolting because they lost everything they owned when they moved and the land owners lost all sources of income (SA History). Sophiatown was a suburb in Johannesburg during the rule of apartheid in South Africa. Sophiatown was the only place in Johannesburg that the government didnt own and exert its discriminatory rules over during the apartheid. However, after Johannesburg grew closer to Sophiatown the government decided to destroy it and relocate the entire population to Soweto. The results of the destruction of Sophiatown were revolts that occurred both in Johannesburg and is Soweto where the people were relocated to. The destruction of Sophiatown helped cause the end of apartheid and developed a specific culture of its own.